Search on:
COMPLEMENT C3B
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
Complement C3b
Descriptor
Spanish
:
Complemento C3b
Descriptor
Portuguese
:
Complemento C3b
Tree Number:
D12.776.124.486.274.250.260
Definition
English
:
The larger fragment generated from the cleavage of
COMPLEMENT C3
by C3 CONVERTASE. It is a constituent of the ALTERNATIVE PATHWAY C3 CONVERTASE (C3bBb), and
COMPLEMENT C5
CONVERTASES in both the classical (C4b2a3b) and the alternative (C3bBb3b) pathway. C3b participates in
IMMUNE ADHERENCE REACTION
and enhances
PHAGOCYTOSIS
. It can be inactivated (iC3b) or cleaved by various proteases to yield fragments such as
COMPLEMENT C3C
;
COMPLEMENT C3D
; C3e; C3f; and C3g.
Indexing Annotation
English
:
/antag: consider
COMPLEMENT C3B INACTIVATOR PROTEINS
Pharmacological Action:
Immunologic Factors
See Related
English
:
Receptors, Complement 3b
History Note
English
:
2006 (1978)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
22315
Unique Identifier:
D003179
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS